Global profiling of lysine lactylation in human lungs
PMID: 37170646
DOI: 10.1002/pmic.202200437
Authors: Yang YH, Wang QC, Kong J, Yang JT, Liu JF
Journal: Proteomics (2023)
37170646_homo_sapiens — Homo sapiens
| Tissue or cell | Normal human lung tissue |
|---|---|
| Condition | Normal physiological condition; selected analyses compared male and female samples |
| Enrichment method | Immunoaffinity enrichment of lactylated peptides; antibody details Not reported |
| MS instrument | Q Exactive Plus |
| Search software | MaxQuant |
| Localization threshold | Class I sites; localization probability threshold was Not reported |
| FDR | Peptide FDR 1% |
| Source-reported sites / proteins | 724 / 451 |
| KlaDB-retained sites / proteins | 610 / 329 |
| Evidence source | 16 local files; primary article/source file: Proteomics - 2023 - Yang - Global profiling of lysine lactylation in human lungs.pdf |
| Curation notes | The current KlaDB count is lower than the source report. Record losses from UniProt mapping, residue validation, filtering, and within-study deduplication.; Repository/accession: PXD036307, PXD036439, iprox; Additional criterion: Quantifiable Class I subset: 614 sites on 333 proteins |