Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells
PMID: 38155775
DOI: 10.1016/j.isci.2023.108645
Authors: Cheng Z, Huang H, Li M, Chen Y
Journal: iScience (2024)
38155775_homo_sapiens — Homo sapiens
| Tissue or cell | FHC normal colonic epithelial cells and SW480 colorectal cancer cells |
|---|---|
| Condition | FHC versus SW480 |
| Enrichment method | Affinity enrichment of lactylated peptides |
| MS instrument | LC-MS/MS; instrument model Not reported |
| Search software | MaxQuant 2.x |
| Localization threshold | Not reported |
| FDR | Peptide and protein FDR 1% |
| Source-reported sites / proteins | 637 / 444 |
| KlaDB-retained sites / proteins | 619 / 432 |
| Evidence source | 3 local files; primary article/source file: main.pdf |
| Curation notes | The current KlaDB count is lower than the source report. Record losses from UniProt mapping, residue validation, filtering, and within-study deduplication.; Repository/accession: IPX0005142001, iProx; Additional criterion: 637 sites on 444 proteins were quantified |