Lysine lactylation-based insight to understanding the characterization of cervical cancer
PMID: 39025375
DOI: 10.1016/j.bbadis.2024.167356
Authors: He C, Zhang J, Bai X, Lu C, Zhang K
Journal: Biochimica et biophysica acta. Molecular basis of disease (2024)
39025375_homo_sapiens — Homo sapiens
| Tissue or cell | HeLa cells; cervical-cancer multi-omics cohorts were used for downstream analyses |
|---|---|
| Condition | HeLa lactylome profiling and integrative cervical-cancer analyses |
| Enrichment method | Kla affinity enrichment |
| MS instrument | LC-MS/MS; instrument model Not reported |
| Search software | Proteome Discoverer 2.x |
| Localization threshold | Not reported |
| FDR | Not reported |
| Source-reported sites / proteins | 3633 / 1637 |
| KlaDB-retained sites / proteins | 3285 / 1556 |
| Evidence source | 13 local files; primary article/source file: 1-s2.0-S0925443924003491-main.pdf |
| Curation notes | The current KlaDB count is lower than the source report. Record losses from UniProt mapping, residue validation, filtering, and within-study deduplication.; Additional criterion: 1,152 stable/quantifiable lactylated proteins after abundance normalization |