Systematic analysis of lysine lactylation in nucleus pulposus cells
PMID: 39524337
DOI: 10.1016/j.isci.2024.111157
Authors: Sheng L, Xu H, Wang Y, Ni J, Xiang T et al
Journal: iScience (2024)
39524337_rattus_norvegicus — Rattus norvegicus
| Tissue or cell | Rat nucleus pulposus cells |
|---|---|
| Condition | Normoxia versus hypoxia |
| Enrichment method | Kla affinity enrichment |
| MS instrument | LC-MS/MS; instrument model Not reported |
| Search software | MaxQuant 1.x |
| Localization threshold | Localization probability >75% |
| FDR | Not reported |
| Source-reported sites / proteins | 3510 / 1052 |
| KlaDB-retained sites / proteins | 3814 / 1254 |
| Evidence source | 3 local files; primary article/source file: main.pdf |
| Curation notes | The current database-linked count exceeds the source report. Investigate PMID propagation across merged sites and rebuild normalized site-level evidence links.; Repository/accession: PXD048244; Additional criterion: Mass error ≤5 ppm; normoxia-specific 129 sites/18 proteins; hypoxia-specific 117 sites/27 proteins |