Global Profiling of Protein Lactylation in Human Hippocampi
PMID: 39610256
DOI: 10.1002/prca.202400061
Authors: Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al
Journal: Proteomics. Clinical applications (2025)
39610256_homo_sapiens — Homo sapiens
| Tissue or cell | Normal human hippocampal tissue |
|---|---|
| Condition | Normal physiological condition |
| Enrichment method | Affinity enrichment of lactylated peptides; antibody details Not reported |
| MS instrument | Orbitrap Exploris 480 |
| Search software | MaxQuant 1.x |
| Localization threshold | Class I sites; exact probability threshold Not reported |
| FDR | Peptide FDR 1% |
| Source-reported sites / proteins | 2579 / 853 |
| KlaDB-retained sites / proteins | 2556 / 848 |
| Evidence source | 16 local files; primary article/source file: 39610256.pdf |
| Curation notes | Counts are approximately consistent. Site-level provenance should still be represented through normalized Study and SiteEvidence records.; Repository/accession: PXD050470, iprox; Additional criterion: 2,579 quantifiable Class I sites on 853 proteins |