Global profiling of protein lactylome in porcine granulosa cells
PMID: 40781717
DOI: 10.1186/s13048-025-01762-8
Authors: Fan S, Zhou R, Wen H, Ye H, Ma S et al
Journal: Journal of ovarian research (2025)
40781717_sus_scrofa — Sus scrofa
| Tissue or cell | Porcine ovarian granulosa cells |
|---|---|
| Condition | Global lactylome profiling; reduced lactylation and ferroptosis were examined |
| Enrichment method | Affinity enrichment of Kla peptides |
| MS instrument | Orbitrap platform; exact model Not reported |
| Search software | Not reported |
| Localization threshold | Not reported |
| FDR | FDR <1% |
| Source-reported sites / proteins | 24038 / 6255 |
| KlaDB-retained sites / proteins | 23514 / 6166 |
| Evidence source | 5 local files; primary article/source file: 13048_2025_Article_1762.pdf |
| Curation notes | The current KlaDB count is lower than the source report. Record losses from UniProt mapping, residue validation, filtering, and within-study deduplication.; Repository/accession: iProX; Additional criterion: 24,038 sites on 6,255 proteins were reported |