Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells
PMID: 41696360
DOI: 10.3389/fcimb.2026.1706727
Authors: Wu Q, Li Z, Gong T, Zheng X, Zhou X et al
Journal: Frontiers in cellular and infection microbiology (2026)
41696360_homo_sapiens — Homo sapiens
| Tissue or cell | Human umbilical vein endothelial cells (HUVECs) |
|---|---|
| Condition | Porphyromonas gingivalis infection versus uninfected control |
| Enrichment method | Lactylated-peptide enrichment method Not reported |
| MS instrument | Orbitrap platform; exact model Not reported |
| Search software | Not reported |
| Localization threshold | Not reported |
| FDR | FDR <1% |
| Source-reported sites / proteins | 5788 / 1881 |
| KlaDB-retained sites / proteins | 5777 / 1878 |
| Evidence source | 12 local files; primary article/source file: 41696360.pdf |
| Curation notes | Counts are approximately consistent. Site-level provenance should still be represented through normalized Study and SiteEvidence records.; Repository/accession: PXD073311; Additional criterion: Following infection, 487 sites were upregulated and 598 sites were downregulated |